No. 7 Michigan has lost quarterback Wilton Speight for multiple weeks with an undisclosed injury.
Coach Jim Harbaugh said Monday that John O'Korn will start Saturday night when the Wolverines (4-0, 1-0 Big Ten) play against Michigan State (3-1, 1-0).
Speight was injured in the first quarter of a Sept. 23 victory at Purdue.
Speight left the stadium for X-rays and Harbaugh later referred to it as a "soft tissue" injury.